PPP2R5B antibody (Middle Region)

Catalog No. ABIN5517089

Product Details anti-PPP2R5B Antibody

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP2R5B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RGVLIEPVYP DIIRMISVNI FRTLPPSENP EFDPEEDEPN LEPSWPHLQL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP2R5B

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPP2R5B

Target: PPP2R5B (Protein Phosphatase 2, Regulatory Subunit B', beta (PPP2R5B))

Alternative Name: PPP2R5B (PPP2R5B Products)

Synonyms: B56B antibody, PR61B antibody, B'beta antibody, BC026670 antibody, PPP2R5B antibody, ppp2r5e antibody, protein phosphatase 2 regulatory subunit B'beta antibody, protein phosphatase 2, regulatory subunit B', beta antibody, protein phosphatase 2A regulatory subunit B' antibody, protein phosphatase 2 regulatory subunit B', beta antibody, protein phosphatase 2 regulatory subunit Bbeta antibody, PPP2R5B antibody, Ppp2r5b antibody, ppp2r5b antibody, ppp2r5b.L antibody, PPP2R2B antibody

Background: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily.

Alias Symbols: B56B, PR61B

Protein Size: 167

Gene ID: 5526

NCBI Accession: NM_006244, NP_006235

UniProt: Q15173

Pathways: PI3K-Akt Signaling, ER-Nucleus Signaling