MYST3 antibody (N-Term)

Catalog No. ABIN5517174

Product Details anti-MYST3 Antibody

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYST3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GLDRKTVLEQ LELSVKDGTI LKVSNKGLNS YKDPDNPGRI ALPKPRNHGK

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYST3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MYST3

Target: MYST3 (MYST Histone Acetyltransferase (Monocytic Leukemia) 3 (MYST3))

Alternative Name: MYST3 (MYST3 Products)

Synonyms: bmd antibody, moz antibody, myst3 antibody, DKFZp469B0815 antibody, MOZ antibody, MYST3 antibody, RUNXBP2 antibody, ZC2HC6A antibody, ZNF220 antibody, 1500036M03 antibody, 9930021N24Rik antibody, Myst3 antibody, Zfp220 antibody, Moz antibody, Runxbp2 antibody, Znf220 antibody, K(lysine) acetyltransferase 6A antibody, lysine acetyltransferase 6A antibody, kat6a antibody, KAT6A antibody, Kat6a antibody

Background: This gene encodes a member of the MOZ, YBFR2, SAS2, TIP60 family of histone acetyltransferases. The protein is composed of a nuclear localization domain, a double C2H2 zinc finger domain that binds to acetylated histone tails, a histone acetyl-transferase domain, a glutamate/aspartate-rich region, and a serine- and methionine-rich transactivation domain. It is part of a complex that acetylates lysine-9 residues in histone 3, and in addition, it acts as a co-activator for several transcription factors. Allelic variants of this gene are associated with autosomal dominant mental retardation-32. Alternative splicing results in multiple transcript variants.

Alias Symbols: MOZ, MRD32, MYST3, MYST-3, ZNF220, RUNXBP2, ZC2HC6A

Protein Size: 815

Gene ID: 7994

NCBI Accession: NM_006766, NP_006757

UniProt: A5PLL3

Pathways: Stem Cell Maintenance, Embryonic Body Morphogenesis