CCL23 antibody (Middle Region)

Catalog No. ABIN5517183

Product Details anti-CCL23 Antibody

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCL23 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SADCCISYTP RSIPCSLLES YFETNSECSK PGVIFLTKKG RRFCANPSDK

Characteristics: This is a rabbit polyclonal antibody against CCL23. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human CCL23

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCL23

Target: CCL23 (Chemokine (C-C Motif) Ligand 23 (CCL23))

Alternative Name: CCL23 (CCL23 Products)

Synonyms: CK-BETA-8 antibody, CKb8 antibody, Ckb-8 antibody, Ckb-8-1 antibody, MIP-3 antibody, MIP3 antibody, MPIF-1 antibody, SCYA23 antibody, hmrp-2a antibody, C-C motif chemokine 23 antibody, C-C motif chemokine ligand 23 antibody, chemokine (C-C motif) ligand 23 antibody, LOC508666 antibody, CCL23 antibody

Background: This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Alias Symbols: CCL23, MIP3, MPIF1, SCYA23,

Protein Interaction Partner: CCR1,

Protein Size: 120

Gene ID: 6368

NCBI Accession: NP_665905

UniProt: P55773