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RASGRP2 antibody (Middle Region)

RASGRP2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5517288
  • Target See all RASGRP2 Antibodies
    RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
    Binding Specificity
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 18
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 15
    • 3
    Rabbit
    Clonality
    • 16
    • 2
    Polyclonal
    Conjugate
    • 18
    This RASGRP2 antibody is un-conjugated
    Application
    • 16
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    RPPVQANPDL LSLLTVSLDQ YQTEDELYQL SLQREPRSKS SPTSPTSCTP
    Purification
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human RASGRP2
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    Discover our top product RASGRP2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    RASGRP2 (RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2))
    Alternative Name
    RASGRP2 (RASGRP2 Products)
    Synonyms
    CALDAG-GEFI antibody, CDC25L antibody, xrasgrp2 antibody, RASGRP2 antibody, Caldaggef1 antibody, CalDAG-GEFI antibody, rasgrp2 antibody, RAS guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) S homeolog antibody, RAS, guanyl releasing protein 2 antibody, RAS guanyl releasing protein 2 (calcium and DAG-regulated) L homeolog antibody, RASGRP2 antibody, rasgrp2.S antibody, Rasgrp2 antibody, rasgrp2.L antibody
    Background
    The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Four alternatively spliced transcript variants encoding two different isoforms have been found for this gene.

    Alias Symbols: CDC25L, CALDAG-GEFI

    Protein Size: 609
    Gene ID
    10235
    NCBI Accession
    NM_001098670, NP_001092140
    UniProt
    Q7LDG7
    Pathways
    TCR Signaling
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