STOML2 antibody (Middle Region)

Catalog No. ABIN5517342

Product Details anti-STOML2 Antibody

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STOML2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LRIMDPYKAS YGVEDPEYAV TQLAQTTMRS ELGKLSLDKV FRERESLNAS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle terminal region of human STOML2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STOML2

Target: STOML2 (Stomatin (EPB72)-Like 2 (STOML2))

Alternative Name: STOML2 (STOML2 Products)

Synonyms: zgc:63505 antibody, MGC116533 antibody, 0610038F01Rik antibody, MSLP2 antibody, SLP-2 antibody, stomatin (EPB72)-like 2 antibody, stomatin like 2 antibody, stomatin like 2 L homeolog antibody, stomatin (Epb7.2)-like 2 antibody, stoml2 antibody, STOML2 antibody, stoml2.L antibody, Stoml2 antibody

Background: Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.

Alias Symbols: SLP-2, HSPC108

Protein Size: 356

Gene ID: 30968

NCBI Accession: NM_001287031, NP_001273961

UniProt: Q9UJZ1

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection