PLA2R1 antibody (Middle Region)

Catalog No. ABIN5517347

Product Details anti-PLA2R1 Antibody

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLA2R1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DENASETWIG LSSNKIPVSF EWSNDSSVIF TNWHTLEPHI FPNRSQLCVS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLA2R1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PLA2R1

Target: PLA2R1 (phospholipase A2 Receptor 1, 180kDa (PLA2R1))

Alternative Name: PLA2R1 (PLA2R1 Products)

Synonyms: Pla2-r antibody, Pla2g1br antibody, Pla2r antibody, CLEC13C antibody, PLA2-R antibody, PLA2G1R antibody, PLA2IR antibody, PLA2R antibody, phospholipase A2 receptor 1 antibody, PLA2R1 antibody, Pla2r1 antibody

Background: This gene represents a phospholipase A2 receptor. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified.

Alias Symbols: PLA2R, PLA2-R, PLA2IR, CLEC13C, PLA2G1R

Protein Size: 167

Gene ID: 22925

NCBI Accession: NM_001007267, NP_001007268

UniProt: Q13018

Pathways: Positive Regulation of Response to DNA Damage Stimulus