TMPRSS2 antibody (Middle Region)

Catalog No. ABIN5517359

Product Details anti-TMPRSS2 Antibody

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFMFYGAGYQ VEKVISHPNY DSKTKNNDIA LMKLQKPLTF NDLVKPVCLP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TMPRSS2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TMPRSS2

Target: TMPRSS2 (Transmembrane Protease, serine 2 (TMPRSS2))

Alternative Name: TMPRSS2 (TMPRSS2 Products)

Synonyms: PP9284 antibody, PRSS10 antibody, D16Ertd61e antibody, transmembrane protease serine 2-like antibody, transmembrane protease, serine 2 antibody, LOC100739411 antibody, TMPRSS2 antibody, Tmprss2 antibody

Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: PP9284, PRSS10

Protein Size: 492

Gene ID: 7113

NCBI Accession: NM_001135099, NP_001128571

UniProt: O15393

Pathways: SARS-CoV-2 Protein Interactome