USP6 antibody (Ubiquitin Specific Peptidase 6) (C-Term)

Details for Product anti-USP6 Antibody No. ABIN5517377
Antigen
Epitope
C-Term
27
21
7
4
1
1
1
1
1
Reactivity
Human
63
11
9
2
2
2
2
1
1
Host
Rabbit
47
14
2
Clonality
Polyclonal
Conjugate
This USP6 antibody is un-conjugated
8
7
7
6
6
6
1
1
1
1
1
1
Application
Western Blotting (WB)
51
40
16
16
1
1
Options
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human USP6
Sequence DHEVALANGF LYEHEACGNG CGDGYSNGQL GNHSEEDSTD DQREDTHIKP
Purification Affinity purified
Antigen
Alternative Name USP6 (USP6 Antibody Abstract)
Background Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.

Alias Symbols: HRP1, TRE2, TRE17, Tre-2, TRESMCR, USP6-short

Protein Size: 1406
Gene ID 9098
NCBI Accession NM_001304284, NP_001291213
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.