PSPC1 antibody (C-Term)

Catalog No. ABIN5517467

Product Details anti-PSPC1 Antibody

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSPC1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QMGSPMGSRT GSETPQAPMS GVGPVSGGPG GFGRGSQGGN FEGPNKRRRY

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the c terminal region of human PSPC1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Alternative Name: PSPC1 (PSPC1 Products)

Synonyms: rexp86 antibody, PSP1 antibody, fj85a06 antibody, wu:fj85a06 antibody, zgc:136470 antibody, 5730470C09Rik antibody, AI327109 antibody, AI449052 antibody, paraspeckle component 1 antibody, paraspeckle component 1 L homeolog antibody, paraspeckle protein 1 antibody, PSPC1 antibody, Tsp_01792 antibody, pspc1 antibody, pspc1.L antibody, Pspc1 antibody

Background: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

Alias Symbols: PSP1

Protein Size: 523

Gene ID: 55269

NCBI Accession: NM_001042414, NP_001035879

UniProt: Q8WXF1