FAN1 antibody (N-Term)

Catalog No. ABIN5517491

Product Details anti-FAN1 Antibody

Target: FAN1 (FANCD2/FANCI-Associated Nuclease 1 (FAN1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAN1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MMSEGKPPDK KRPRRSLSIS KNKKKASNSI ISCFNNAPPA KLACPVCSKM

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FAN1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FAN1

Target: FAN1 (FANCD2/FANCI-Associated Nuclease 1 (FAN1))

Alternative Name: FAN1 (FAN1 Products)

Synonyms: KIAA1018 antibody, KMIN antibody, MTMR15 antibody, 6030441H18Rik antibody, Mtmr15 antibody, fi39f01 antibody, mtmr15 antibody, si:ch211-163b1.2 antibody, si:ch211-201b11.2 antibody, wu:fd06a07 antibody, wu:fi39f01 antibody, RGD1566323 antibody, FANCD2 and FANCI associated nuclease 1 antibody, FANCD2/FANCI-associated nuclease 1 antibody, FAN1 antibody, Fan1 antibody, fan1 antibody

Background: This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Alias Symbols: KMIN, hFAN1, MTMR15, KIAA1018

Protein Size: 533

Gene ID: 22909

NCBI Accession: NM_001146094, NP_001139566

Pathways: DNA Damage Repair