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FAN1 antibody (N-Term)
FAN1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FAN1 Antibody
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Target
See all FAN1 Antibodies
FAN1
(FANCD2/FANCI-Associated Nuclease 1 (FAN1))
Binding Specificity
All epitopes for FAN1 antibodies
N-Term
Reactivity
All reactivities for FAN1 antibodies
Human
Host
All hosts for FAN1 antibodies
Rabbit
Clonality
All clonalities for FAN1 antibodies
Polyclonal
Conjugate
All conjugates for FAN1 antibodies
This FAN1 antibody is un-conjugated
Application
All applications for FAN1 antibodies
Western Blotting (WB)
Sequence
MMSEGKPPDK KRPRRSLSIS KNKKKASNSI ISCFNNAPPA KLACPVCSKM
Purification
Affinity purified
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human FAN1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target Details for FAN1
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Target
FAN1
(FANCD2/FANCI-Associated Nuclease 1 (FAN1))
Alternative Name
FAN1 (FAN1 Products )
Synonyms
KIAA1018 antibody, KMIN antibody, MTMR15 antibody, 6030441H18Rik antibody, Mtmr15 antibody, fi39f01 antibody, mtmr15 antibody, si:ch211-163b1.2 antibody, si:ch211-201b11.2 antibody, wu:fd06a07 antibody, wu:fi39f01 antibody, RGD1566323 antibody, FANCD2 and FANCI associated nuclease 1 antibody, FANCD2/FANCI-associated nuclease 1 antibody, FAN1 antibody, Fan1 antibody, fan1 antibody
Background
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alias Symbols: KMIN, hFAN1, MTMR15, KIAA1018 Protein Size: 533
Gene ID
22909
NCBI Accession
NM_001146094 , NP_001139566
Pathways
DNA Damage Repair
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