RNPS1 antibody (N-Term)

Catalog No. ABIN5517572

Product Details anti-RNPS1 Antibody

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNPS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PTKRKDRSDE KSKDRSKDKG ATKESSEKDR GRDKTRKRRS ASSGSSSTRS

Characteristics: This is a rabbit polyclonal antibody against RNPS1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RNPS1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNPS1

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Alternative Name: RNPS1 (RNPS1 Products)

Synonyms: E5.1 antibody, ribonucleic acid binding protein S1 antibody, RNA binding protein with serine rich domain 1 antibody, RNA binding protein S1, serine-rich domain antibody, Rnps1 antibody, RNPS1 antibody

Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RNPS1, LDC2,

Protein Interaction Partner: CLK2, HEXIM2, TRIM41, SDCBP2, ZNF473, U2AF1, SRPK2, ZBTB14, UBC, SUZ12, RNF2, BMI1, PIN1, SRPK1, UPF2, CSNK2A2, LUC7L3, TRA2A, ACIN1, TAF2, SRP54, TRA2B, SRSF4, SRSF1, PNN, Dlg4, PRPF38A, CHERP, EIF4A3, MAGOH, WIBG, UPF3B, SMU1, PRPF19, GNL3, RALY, SAP18,

Protein Size: 305

Gene ID: 10921

NCBI Accession: XP_005255106

UniProt: Q15287