TRMT12 antibody (Middle Region)

Catalog No. ABIN5517583

Product Details anti-TRMT12 Antibody

Target: TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRMT12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KEHWLYPQQI TTNQWKNGAT RDSRGKMLSP ATKPEWQRWA ESAETRIATL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TRMT12

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TRMT12

Target: TRMT12 (tRNA Methyltransferase 12 Homolog (TRMT12))

Alternative Name: TRMT12 (TRMT12 Products)

Synonyms: 4632406N01Rik antibody, AI449275 antibody, Tyw2 antibody, TRM12 antibody, TYW2 antibody, RGD1307127 antibody, trmt12 antibody, tRNA methyltranferase 12 antibody, tRNA methyltransferase 12 homolog antibody, tRNA methyltransferase 12 antibody, tRNA methyltransferase 12 homolog (S. cerevisiae) antibody, Trmt12 antibody, TRMT12 antibody, trmt12 antibody

Background: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

Alias Symbols: TYW2, TRM12

Protein Size: 448

Gene ID: 55039

NCBI Accession: NM_017956, NP_060426

UniProt: Q53H54