VAC14 antibody (C-Term)

Catalog No. ABIN5517585

Product Details anti-VAC14 Antibody

Target: VAC14 (Vac14 Homolog (VAC14))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LKDLEVLAEI ASSPAGQTDD PGPLDGPDLQ ASHSELQVPT PGRAGLLNTS

Characteristics: This is a rabbit polyclonal antibody against VAC14. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human VAC14

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14 (VAC14 Products)

Synonyms: ArPIKfyve antibody, TAX1BP2 antibody, TRX antibody, AA959718 antibody, BC032215 antibody, D8Wsu151e antibody, Tax1bp2 antibody, Trx antibody, ingls antibody, Vac14 homolog L homeolog antibody, Vac14, PIKFYVE complex component antibody, Vac14 homolog (S. cerevisiae) antibody, vac14.L antibody, VAC14 antibody, Vac14 antibody

Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE.

Alias Symbols: TAX1BP2, TRX

Protein Size: 782

Gene ID: 55697

NCBI Accession: NP_060522

UniProt: Q08AM6

Pathways: Inositol Metabolic Process