PES1 antibody (Middle Region)

Catalog No. ABIN5517691

Product Details anti-PES1 Antibody

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PES1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LLALQRGEDP GNLNESEEEE EEDDNNEGDG DEEGENEEEE EDAEAGSEKE

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PES1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PES1

Target: PES1 (Pescadillo Ribosomal Biogenesis Factor 1 (PES1))

Alternative Name: PES1 (PES1 Products)

Synonyms: PES antibody, pes antibody, pes1 antibody, pescadillo ribosomal biogenesis factor 1 antibody, pescadillo ribosomal biogenesis factor 1 S homeolog antibody, Pescadillo antibody, PES1 antibody, Pes1 antibody, pes1.S antibody, pesc antibody

Background: This gene encodes a nuclear protein that contains a breast cancer associated gene 1 (BRCA1) C-terminal interaction domain. The encoded protein interacts with BOP1 and WDR12 to form the PeBoW complex, which plays a critical role in cell proliferation via pre-rRNA processing and 60S ribosomal subunit maturation. Expression of this gene may play an important role in breast cancer proliferation and tumorigenicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the long arm of chromosome 4 and the short arm of chromosome 9.

Alias Symbols: PES

Protein Size: 167

Gene ID: 23481

NCBI Accession: NM_001243225, NP_001230154

UniProt: O00541