MMAB antibody (Middle Region)

Catalog No. ABIN5517725

Product Details anti-MMAB Antibody

Target: MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MMAB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRIPKIYTKT GDKGFSSTFT GERRPKDDQV FEAVGTTDEL SSAIGFALEL

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human MMAB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MMAB

Target: MMAB (Methylmalonic Aciduria (Cobalamin Deficiency) CblB Type (MMAB))

Alternative Name: MMAB (MMAB Products)

Synonyms: ATR antibody, cblB antibody, cob antibody, 9130222L19Rik antibody, methylmalonic aciduria (cobalamin deficiency) cblB type antibody, methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human) antibody, MMAB antibody, Mmab antibody

Background: This gene encodes a protein that catalyzes the final step in the conversion of vitamin B(12) into adenosylcobalamin (AdoCbl), a vitamin B12-containing coenzyme for methylmalonyl-CoA mutase. Mutations in the gene are the cause of vitamin B12-dependent methylmalonic aciduria linked to the cblB complementation group. Alternatively spliced transcript variants have been found.

Alias Symbols: ATR, cob, cblB, CFAP23

Protein Size: 173

Gene ID: 326625

NCBI Accession: NP_443077

UniProt: F5H4Z7