SEH1L antibody (N-Term)

Catalog No. ABIN5517747

Product Details anti-SEH1L Antibody

Target: SEH1L (SEH1-Like (SEH1L))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEH1L antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FDRTAAVWEE IVGESNDKLR GQSHWVKRTT LVDSRTSVTD VKFAPKHMGL

Characteristics: This is a rabbit polyclonal antibody against SEH1. It was validated on Western Blot.

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SEH1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEH1L

Target: SEH1L (SEH1-Like (SEH1L))

Alternative Name: SEH1 (SEH1L Products)

Synonyms: 2610007A16Rik antibody, AW540070 antibody, SEC13L antibody, SEH1A antibody, SEH1B antibody, Seh1 antibody, seh1l-a antibody, fa02g03 antibody, wu:fa02g03 antibody, zgc:55977 antibody, SEH1-like (S. cerevisiae antibody, SEH1 like nucleoporin antibody, SEH1 like nucleoporin L homeolog antibody, SEH1-like (S. cerevisiae) antibody, Seh1l antibody, SEH1L antibody, seh1l.L antibody, seh1l antibody

Background: The protein encoded by this gene is part of a nuclear pore complex, Nup107-160. This protein contains WD repeats and shares 34 % amino acid identity with yeast Seh1 and 30 % identity with yeast Sec13. All constituents of the Nup107-160 complex, including this protein, specifically localize to kinetochores in mitosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alias Symbols: SEH1L, SEC13L, SEH1,

Protein Interaction Partner: SUMO2, SUMO1, RPA3, RPA2, RPA1, NUP43, DCTN4, NUP160, DCTN2, NUP37, ACTR1B, HECW2, env, UBC, ATP6V0A1, NUP107, COPS5, ELAVL1, Nup98, SAP25, BECN1, USP32P2, RAE1, NUP85, NUP133,

Protein Size: 360

Gene ID: 81929

NCBI Accession: NP_112493

UniProt: Q96EE3

Pathways: Maintenance of Protein Location