SIM2 antibody (Middle Region)
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- Target See all SIM2 Antibodies
- SIM2 (Single-Minded Homolog 2 (SIM2))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Cow, Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SIM2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.
- Purification
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human SIM2
- Top Product
- Discover our top product SIM2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Alternative Name
- SIM2 (SIM2 Products)
- Synonyms
- Xsim2 antibody, sim2-A antibody, xSim antibody, HMC13F06 antibody, HMC29C01 antibody, SIM antibody, bHLHe15 antibody, single-minded family bHLH transcription factor 2 S homeolog antibody, single-minded family bHLH transcription factor 2 antibody, single-minded homolog 2 (Drosophila) antibody, sim2.S antibody, sim2 antibody, SIM2 antibody, Sim2 antibody
- Background
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2, BHLHE15,
Protein Size: 667 - Gene ID
- 6493
- UniProt
- Q14190
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