ARP8 Actin-Related Protein 8 Homolog (Yeast) (ACTR8) (Middle Region) antibody

Details for Product No. ABIN5517918
Antigen
Epitope
Middle Region
4
2
Reactivity
Human
6
1
1
1
1
1
1
Host
Rabbit
6
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
Application
Western Blotting (WB)
4
3
Options
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ACTR8
Sequence TLQHRSQGDP EDPHDEHYLL ATQSKQEQSA KATADRKSAS KPIGFEGDLR
Purification Affinity purified
Antigen
Alternative Name ACTR8 (ACTR8 Antibody Abstract)
Background Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize.Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA reoplication and probably DNA repair. Required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage. Strongly prefer nucleosomes and H3-H4 tetramers over H2A-H2B dimers, suggesting it may act as a nucleosome recognition module within the complex.

Alias Symbols: ARP8, hArp8, INO80N

Protein Size: 513
Gene ID 93973
NCBI Accession NM_022899, NP_075050
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Format Liquid
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.