Syndecan 1 antibody (AA 23-254)

Catalog No. ABIN5518953

Product Details anti-Syndecan 1 Antibody

Target: Syndecan 1 (SDC1)

Binding Specificity: AA 23-254

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syndecan 1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Syndecan-1(SDC1) detection. Tested with WB in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Syndecan-1(SDC1) detection. Tested with WB in Human.
Gene Name: syndecan 1
Protein Name: Syndecan-1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Syndecan-1/SDC1 recombinant protein (Position: Q23-G254). Human Syndecan-1/SDC1 shares 69.2% and 69.8% amino acid (aa) sequence identity with mouse and rat Syndecan-1/SDC1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

References for anti-Syndecan 1 antibody (ABIN5518953)

Huang, Zhu, Zhang, Zhu, Liu, Zhu, Wang, Li, Yang, Dong, Liu, Chen, Zhang, Yang, Deng, Fan, Wang, Liu, Ma, Fu, Wu: "S100+ cells: a new neuro-immune cross-talkers in lymph organs." in: Scientific reports, Vol. 3, pp. 1114, (2013) (PubMed).

Target Details for Syndecan 1

Target: Syndecan 1 (SDC1)

Alternative Name: SDC1 (SDC1 Products)

Synonyms: CG10497 antibody, CT27296 antibody, Dmel\\CG10497 antibody, Dsyn antibody, Syd antibody, Syn antibody, dSdc antibody, l(2)10608 antibody, sdc antibody, syd antibody, syn antibody, Syn1 antibody, cd138 antibody, synd1 antibody, xSyn1 antibody, syndecan1 antibody, Syndecan-1 antibody, XSyndecan-1 antibody, SDC1 antibody, CD138 antibody, SDC antibody, SYND1 antibody, syndecan antibody, AA408134 antibody, AA409076 antibody, Sstn antibody, Synd antibody, Synd1 antibody, syn-1 antibody, HSPG antibody, SYNDECA antibody, Syndecan antibody, Syndecan antibody, syndecan 1 antibody, Sdc antibody, sdc1 antibody, SDC1 antibody, Sdc1 antibody

Background: Syndecan 1 is a protein which in humans is encoded by the SDC1 gene. The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Synonyms: Syndecan-1, SYND1, CD138, SDC1, SDC

Gene ID: 6382

UniProt: P18827

Pathways: Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Lipid Metabolism