ATP2B4 antibody (C-Term)

Catalog No. ABIN5530323

Product Details anti-ATP2B4 Antibody

Target: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Binding Specificity: AA 1174-1202, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP2B4 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATP2B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1174-1202 amino acids from the C-terminal region of human ATP2B4.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ATP2B4

Target: ATP2B4 (ATPase, Ca++ Transporting, Plasma Membrane 4 (ATP2B4))

Alternative Name: ATP2B4 (ATP2B4 Products)

Synonyms: ATP2B2 antibody, MXRA1 antibody, PMCA4 antibody, PMCA4b antibody, PMCA4x antibody, atp2b2 antibody, atp2b3 antibody, mxra1 antibody, pmca4 antibody, pmca4b antibody, pmca4x antibody, zgc:152801 antibody, ATP2B4 antibody, ATP2B1 antibody, Pmca4 antibody, ATPase plasma membrane Ca2+ transporting 4 antibody, ATPase, Ca++ transporting, plasma membrane 4 L homeolog antibody, ATPase, Ca++ transporting, plasma membrane 4 antibody, ATP2B4 antibody, atp2b4.L antibody, atp2b4 antibody, Atp2b4 antibody

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].

Molecular Weight: 138 kDa

Gene ID: 493

UniProt: P23634

Pathways: Ribonucleoside Biosynthetic Process