Biglycan antibody (AA 148-176)

Catalog No. ABIN5530519

Product Details anti-Biglycan Antibody

Target: Biglycan (BGN)

Binding Specificity: AA 148-176

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Biglycan antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This BGN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the Central region of human BGN.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Biglycan

Target: Biglycan (BGN)

Alternative Name: BGN (BGN Products)

Synonyms: DSPG1 antibody, PG-S1 antibody, PGI antibody, SLRR1A antibody, BG antibody, BSPG1 antibody, bgn antibody, zgc:91989 antibody, dspg1 antibody, pg-s1 antibody, slrr1a antibody, xbgn antibody, BGN antibody, zgc:77123 antibody, DKFZp468I2427 antibody, biglycan antibody, biglycan L homeolog antibody, biglycan a antibody, biglycan S homeolog antibody, biglycan b antibody, BGN antibody, Bgn antibody, bgn.L antibody, bgna antibody, bgn.S antibody, bgn antibody, bgnb antibody

Background: BGN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein is thought to function in connective tissue metabolism by binding to collagen fibrils and transfering growth factor-beta. It may promote neuronal survival.

Molecular Weight: 42 kDa

Gene ID: 633

UniProt: P21810

Pathways: Glycosaminoglycan Metabolic Process