BMP1 antibody (C-Term)

Catalog No. ABIN5530531

Product Details anti-BMP1 Antibody

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Binding Specificity: AA 957-986, C-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This Bmp1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 957-986 amino acids from the C-terminal region of human Bmp1.

Isotype: Ig Fraction

Application Details

Application Notes: For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for BMP1

Target: BMP1 (Bone Morphogenetic Protein 1 (BMP1))

Alternative Name: Bmp1 (BMP1 Products)

Synonyms: OI13 antibody, PCOLC antibody, PCP antibody, PCP2 antibody, TLD antibody, Pcp antibody, Tld antibody, BMP1 antibody, submp antibody, tld antibody, xtld antibody, bmp-1 antibody, pcolc antibody, xbmp1 antibody, tolloid antibody, BMP-1 antibody, bmp1 antibody, bmp1a antibody, bone morphogenetic protein 1 antibody, Bone morphogenetic protein 1 antibody, bone morphogenetic protein 1 S homeolog antibody, bone morphogenetic protein 1, like antibody, BMP1 antibody, Bmp1 antibody, bmp1 antibody, bmp1.S antibody, bmp1l antibody

Background: The BMP1 locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members of the TGF-beta superfamily, BMP1 encodes a protein that is not closely related to other known growth factors. BMP1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.

Molecular Weight: 111 kDa

Gene ID: 649

UniProt: P13497

Pathways: Lipid Metabolism