COL6A1 antibody (C-Term)

Catalog No. ABIN5530852

Product Details anti-COL6A1 Antibody

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Binding Specificity: AA 831-858, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL6A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This COL6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-858 amino acids from the C-terminal region of human COL6A1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:500-1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for COL6A1

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Alternative Name: COL6A1 (COL6A1 Products)

Synonyms: CBR antibody, SDR21C1 antibody, hCBR1 antibody, OPLL antibody, AI747156 antibody, Col6a-1 antibody, RGD1565398 antibody, COL6A1 antibody, carbonyl reductase 1 antibody, collagen type VI alpha 1 chain antibody, collagen, type VI, alpha 1 antibody, collagen, type VI, alpha 1 L homeolog antibody, collagen type VI alpha 3 chain antibody, collagen alpha-1(VI) chain antibody, CBR1 antibody, COL6A1 antibody, Col6a1 antibody, col6a1.L antibody, COL6A3 antibody, col6a1 antibody, LOC100623720 antibody

Background: The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.

Molecular Weight: 109 kDa

Gene ID: 1291

UniProt: P12109

Pathways: Growth Factor Binding, SARS-CoV-2 Protein Interactome