DAZ2 antibody (Deleted in Azoospermia 2) (AA 518-546)

Details for Product anti-DAZ2 Antibody No. ABIN5531056
Antigen
Epitope
AA 518-546, C-Term
9
9
8
6
2
2
1
1
1
1
Reactivity
Human
37
7
7
1
1
1
1
1
1
Host
Rabbit
37
Clonality
Polyclonal
Conjugate
This DAZ2 antibody is un-conjugated
4
4
2
2
2
2
Application
Western Blotting (WB)
36
16
5
3
3
2
1
1
Options
Immunogen This DAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 518-546 amino acids from the C-terminal region of human DAZ2.
Isotype Ig Fraction
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Antigen
Alternative Name DAZ2 (DAZ2 Antibody Abstract)
Background This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Molecular Weight 63 kDa
Gene ID 57055
UniProt Q13117
Application Notes For WB starting dilution is: 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Supplier Images
Image no. 1 for anti-Deleted in Azoospermia 2 (DAZ2) (AA 518-546), (C-Term) antibody (ABIN5531056) Western blot analysis in 293 cell line lysates (35ug/lane).