Desmocollin 3 antibody (C-Term)

Catalog No. ABIN5531059

Product Details anti-Desmocollin 3 Antibody

Target: Desmocollin 3 (DSC3)

Binding Specificity: AA 822-850, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Desmocollin 3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DSC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 822-850 amino acids from the C-terminal region of human DSC3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Desmocollin 3

Target: Desmocollin 3 (DSC3)

Alternative Name: DSC3 (DSC3 Products)

Synonyms: CDHF3 antibody, DSC antibody, DSC1 antibody, DSC2 antibody, DSC4 antibody, HT-CP antibody, 5430426I24Rik antibody, MGC85083 antibody, desmocollin 3 antibody, desmocollin 3 S homeolog antibody, DSC3 antibody, Dsc3 antibody, dsc3.S antibody, dsc3 antibody

Background: The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Molecular Weight: 100 kDa

Gene ID: 1825

UniProt: Q14574