HAND2 antibody (AA 81-110)

Catalog No. ABIN5531318

Product Details anti-HAND2 Antibody

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Binding Specificity: AA 81-110

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HAND2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HAND2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-110 amino acids from the Central region of human HAND2.

Isotype: Ig Fraction

Application Details

Application Notes: For IF starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for HAND2

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Alternative Name: HAND2 (HAND2 Products)

Synonyms: DHAND2 antibody, Hed antibody, Thing2 antibody, bHLHa26 antibody, dHand antibody, dhand2 antibody, hand2 antibody, xhand2 antibody, hand2-b antibody, Hand2' antibody, dHAND antibody, HAND2 antibody, hed antibody, dhand antibody, thing2 antibody, LOC100218345 antibody, AI225906 antibody, AI661148 antibody, Ehand2 antibody, Th2 antibody, zdHAND antibody, zgc:103415 antibody, Hand2 antibody, heart and neural crest derivatives expressed 2 antibody, heart and neural crest derivatives expressed 2 L homeolog antibody, heart and neural crest derivatives expressed 2 S homeolog antibody, HAND2 antibody, Hand2 antibody, hand2.L antibody, hand2.S antibody, hand2 antibody

Background: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development.

Molecular Weight: 24 kDa

Gene ID: 9464

UniProt: P61296

Pathways: Tube Formation, Feeding Behaviour