LUM antibody (AA 198-227)

Catalog No. ABIN5531539

Product Details anti-LUM Antibody

Target: LUM (Lumican (LUM))

Binding Specificity: AA 198-227

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LUM antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This LUM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human LUM.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for LUM

Target: LUM (Lumican (LUM))

Alternative Name: LUM (LUM Products)

Synonyms: MGC64527 antibody, zgc:86661 antibody, ldc antibody, slrr2d antibody, DKFZp468L1116 antibody, LDC antibody, SLRR2D antibody, Ldc antibody, lumican antibody, lumican L homeolog antibody, LUM antibody, lum.L antibody, lum antibody, CpipJ_CPIJ010209 antibody, Lum antibody

Background: LUM is a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, this protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. The protein is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair.

Molecular Weight: 38 kDa

Gene ID: 4060

UniProt: P51884

Pathways: Glycosaminoglycan Metabolic Process