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TRKA antibody

NTRK1 Reactivity: Human, Mouse WB, IF, FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5531716
  • Target See all TRKA (NTRK1) Antibodies
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Reactivity
    • 239
    • 151
    • 144
    • 15
    • 4
    • 4
    • 1
    • 1
    Human, Mouse
    Host
    • 248
    • 15
    • 3
    • 2
    Rabbit
    Clonality
    • 240
    • 27
    • 1
    Polyclonal
    Conjugate
    • 102
    • 18
    • 15
    • 13
    • 11
    • 11
    • 11
    • 11
    • 11
    • 11
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRKA antibody is un-conjugated
    Application
    • 185
    • 99
    • 79
    • 78
    • 51
    • 38
    • 30
    • 20
    • 19
    • 14
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This TrkA antibody is generated from rabbits immunized with TrkA his fusion protein
    Isotype
    Ig Fraction
    Top Product
    Discover our top product NTRK1 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For FACS starting dilution is: 1:10~50

    For IF starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    TRKA (NTRK1) (Neurotrophic Tyrosine Kinase, Receptor, Type 1 (NTRK1))
    Alternative Name
    TrkA (NTRK1 Products)
    Synonyms
    MTC antibody, TRK antibody, TRK1 antibody, TRKA antibody, Trk-A antibody, p140-TrkA antibody, CDHF12 antibody, CDHR16 antibody, HSCR1 antibody, MEN2A antibody, MEN2B antibody, MTC1 antibody, PTC antibody, RET-ELE1 antibody, RET51 antibody, Trk antibody, C80751 antibody, Tkr antibody, TrkA antibody, trk antibody, trka antibody, CTRKA antibody, trkA antibody, neurotrophic receptor tyrosine kinase 1 antibody, ret proto-oncogene antibody, neurotrophic tyrosine kinase, receptor, type 1 antibody, NTRK1 antibody, RET antibody, Ntrk1 antibody, ntrk1 antibody
    Background
    TRKA (also known as NTRK1)is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
    Molecular Weight
    87 kDa
    Gene ID
    4914
    UniProt
    P04629
    Pathways
    RTK Signaling, Neurotrophin Signaling Pathway, cAMP Metabolic Process
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