NR2E3 antibody (AA 170-198)

Catalog No. ABIN5531935

Product Details anti-NR2E3 Antibody

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Binding Specificity: AA 170-198

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NR2E3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NR2E3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human NR2E3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.36 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for NR2E3

Target: NR2E3 (Nuclear Receptor Subfamily 2, Group E, Member 3 (NR2E3))

Alternative Name: NR2E3 (NR2E3 Products)

Synonyms: ESCS antibody, PNR antibody, RNR antibody, RP37 antibody, rd7 antibody, LOC100228348 antibody, A930035N01Rik antibody, wu:fj55b07 antibody, zgc:103631 antibody, nuclear receptor subfamily 2 group E member 3 antibody, nuclear receptor subfamily 2, group E, member 3 antibody, NR2E3 antibody, Nr2e3 antibody, nr2e3 antibody

Background: This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Molecular Weight: 45 kDa

Gene ID: 10002

UniProt: Q9Y5X4

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway