PCDHAC2 antibody (AA 616-644)

Catalog No. ABIN5531978

Product Details anti-PCDHAC2 Antibody

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Binding Specificity: AA 616-644

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHAC2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PCDHAC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 616-644 amino acids from the Central region of human PCDHAC2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for PCDHAC2

Target: PCDHAC2 (Protocadherin alpha Subfamily C, 2 (PCDHAC2))

Alternative Name: PCDHAC2 (PCDHAC2 Products)

Synonyms: PCDH-ALPHA-C2 antibody, CNRc2 antibody, rCNRvc2 antibody, CNRC02 antibody, PCHD antibody, protocadherin alpha subfamily C, 2 antibody, PCDHAC2 antibody, Pcdhac2 antibody, pcdhac2 antibody

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Molecular Weight: 109 kDa

Gene ID: 56134

UniProt: Q9Y5I4