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SAFB antibody (N-Term)

SAFB Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5532095
  • Target See all SAFB Antibodies
    SAFB (Scaffold Attachment Factor B (SAFB))
    Binding Specificity
    • 15
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-94, N-Term
    Reactivity
    • 40
    • 22
    • 17
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 10
    Rabbit
    Clonality
    • 44
    • 11
    Polyclonal
    Conjugate
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SAFB antibody is un-conjugated
    Application
    • 38
    • 21
    • 14
    • 14
    • 13
    • 12
    • 9
    • 9
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This SAFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 65-94 amino acids from the N-terminal region of human SAFB.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product SAFB Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    SAFB (Scaffold Attachment Factor B (SAFB))
    Alternative Name
    SAFB (SAFB Products)
    Synonyms
    HAP antibody, HET antibody, SAF-B1 antibody, SAFB1 antibody, 3110021E02Rik antibody, 5330423C17Rik antibody, AU018122 antibody, D18386 antibody, E130307D12 antibody, zgc:55387 antibody, wu:fb40a03 antibody, wu:fd42g06 antibody, SAFB2 antibody, SAFB antibody, scaffold attachment factor B antibody, scaffold attachment factor B S homeolog antibody, SAFB-like transcription modulator antibody, Scaffold attachment factor B antibody, SAFB antibody, Safb antibody, safb antibody, safb.S antibody, LOC5570070 antibody, CpipJ_CPIJ017179 antibody, Bm1_49330 antibody, LOAG_00080 antibody
    Background
    This gene encodes a DNA-binding protein that has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. This encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of the heat shock protein 27 transcription and also can act as an estrogen receptor corepressor. This gene is a candidate gene for breast tumorigenesis.
    Molecular Weight
    103 kDa
    Gene ID
    6294
    UniProt
    Q15424
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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