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PLAT antibody (AA 371-399)

PLAT Reactivity: Human WB, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5532216
  • Target See all PLAT Antibodies
    PLAT (Plasminogen Activator, Tissue (PLAT))
    Binding Specificity
    • 15
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-399
    Reactivity
    • 74
    • 72
    • 46
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 101
    • 19
    • 11
    • 2
    • 1
    Rabbit
    Clonality
    • 113
    • 20
    Polyclonal
    Conjugate
    • 58
    • 16
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PLAT antibody is un-conjugated
    Application
    • 101
    • 55
    • 36
    • 26
    • 26
    • 15
    • 14
    • 12
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
    Immunogen
    This TPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-399 amino acids from the Central region of human TPA.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PLAT Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For FACS starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    2 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PLAT (Plasminogen Activator, Tissue (PLAT))
    Alternative Name
    TPA (PLAT Products)
    Synonyms
    T-PA antibody, TPA antibody, AU020998 antibody, AW212668 antibody, D8Ertd2e antibody, tPA antibody, PATISS antibody, tpa antibody, Plat antibody, plat antibody, t-pa antibody, plasminogen activator, tissue type antibody, plasminogen activator, tissue antibody, chromosome 20 open reading frame 181 antibody, plasminogen activator, tissue L homeolog antibody, PLAT antibody, Plat antibody, plat antibody, C20orf181 antibody, plat.L antibody
    Background
    TPA is a tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism.
    Molecular Weight
    63 kDa
    Gene ID
    5327
    UniProt
    P00750
    Pathways
    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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