TFEC antibody (AA 179-205)

Catalog No. ABIN5532243

Product Details anti-TFEC Antibody

Target: TFEC (Transcription Factor EC (TFEC))

Binding Specificity: AA 179-205

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEC antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TFEC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-205 amino acids from the Central region of human TFEC.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for TFEC

Target: TFEC (Transcription Factor EC (TFEC))

Alternative Name: TFEC (TFEC Products)

Synonyms: si:ch211-238e6.5 antibody, TFEC antibody, TCFEC antibody, TFE-C antibody, TFEC-L antibody, TFECL antibody, bHLHe34 antibody, hTFEC-L antibody, BB107417 antibody, Tcfec antibody, transcription factor EC antibody, tfec antibody, TFEC antibody, Tfec antibody

Background: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase (TRAP) E-box containing promoter (By similarity). Collaborates with MITF in target gene activation (By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence (By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer (By similarity). Binds DNA in a homo-or heterodimeric form.

Molecular Weight: 39 kDa

Gene ID: 22797

UniProt: O14948