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PCDHGA5 antibody (N-Term)

PCDHGA5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5532675
  • Target See all PCDHGA5 Antibodies
    PCDHGA5 (Protocadherin gamma Subfamily A, 5 (PCDHGA5))
    Binding Specificity
    • 8
    • 7
    • 6
    • 4
    • 1
    • 1
    AA 254-280, N-Term
    Reactivity
    • 22
    • 1
    • 1
    Human
    Host
    • 18
    • 4
    Rabbit
    Clonality
    • 20
    • 2
    Polyclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This PCDHGA5 antibody is un-conjugated
    Application
    • 22
    • 15
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHGA5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-280 amino acids from the N-terminal region of human PCDHGA5.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCDHGA5 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PCDHGA5 (Protocadherin gamma Subfamily A, 5 (PCDHGA5))
    Alternative Name
    PCDHGA5 (PCDHGA5 Products)
    Synonyms
    CDH-GAMMA-A5 antibody, ME3 antibody, PCDH-GAMMA-A5 antibody, protocadherin gamma subfamily A, 5 antibody, protocadherin gamma-A5 antibody, PCDHGA5 antibody, Pcdhga5 antibody, LOC100516665 antibody
    Background
    This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Molecular Weight
    101 kDa
    Gene ID
    56110
    UniProt
    Q9Y5G8
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