ABCD1 antibody (AA 257-285)

Catalog No. ABIN5532772

Product Details anti-ABCD1 Antibody

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Binding Specificity: AA 257-285

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCD1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ABCD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human ABCD1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.32 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ABCD1

Target: ABCD1 (ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1))

Alternative Name: ABCD1 (ABCD1 Products)

Synonyms: ABC42 antibody, ALD antibody, ALDP antibody, AMN antibody, RGD1562128 antibody, zgc:172102 antibody, ABCD1 antibody, Ald antibody, Aldgh antibody, ATP binding cassette subfamily D member 1 antibody, ATP-binding cassette, sub-family D (ALD), member 1 antibody, ATP-binding cassette sub-family D member 1 antibody, ATP binding cassette subfamily D member 1 L homeolog antibody, ABCD1 antibody, Abcd1 antibody, abcd1 antibody, CpipJ_CPIJ013253 antibody, VDBG_05717 antibody, abcd1.L antibody

Background: ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Molecular Weight: 83 kDa

Gene ID: 215

UniProt: P33897

Pathways: Monocarboxylic Acid Catabolic Process