CBX2 antibody (AA 137-166)

Catalog No. ABIN5532849

Product Details anti-CBX2 Antibody

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Binding Specificity: AA 137-166

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-166 amino acids from the Central region of human CBX2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CBX2

Target: CBX2 (Chromobox Homolog 2 (CBX2))

Alternative Name: CBX2 (CBX2 Products)

Synonyms: cbx2 antibody, M33 antibody, pc1 antibody, wu:fd20e09 antibody, zgc:103563 antibody, MOD2 antibody, pc antibody, CDCA6 antibody, SRXY5 antibody, cdca6 antibody, m33 antibody, chromobox 2 antibody, chromobox homolog 2 (Drosophila Pc class) antibody, chromobox 2 L homeolog antibody, cbx2 antibody, CBX2 antibody, Cbx2 antibody, cbx2.L antibody

Background: This gene encodes a component of the polycomb multiprotein complex, which is required to maintain the transcriptionally repressive state of many genes throughout development via chromatin remodeling and modification of histones. Disruption of this gene in mice results in male-to-female gonadal sex reversal. Mutations in this gene are also associated with gonadal dysgenesis in humans. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Molecular Weight: 56 kDa

Gene ID: 84733

UniProt: Q14781