This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human ASAP1.
ASAP1
Reactivity: Human
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Application Notes
For WB starting dilution is: 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
Supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Target
ASAP1
(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
AV239055 antibody, DEF-1 antibody, Ddef1 antibody, PAP antibody, mKIAA1249 antibody, s19 antibody, AMAP1 antibody, CENTB4 antibody, DDEF1 antibody, PAG2 antibody, ZG14P antibody, ASAP1 antibody, ddef1 antibody, Asap1 antibody, si:ch211-160i2.3 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain1 antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 antibody, toxic extracellular endopeptidase antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog antibody, ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a antibody, Asap1 antibody, ASAP1 antibody, asaP1 antibody, asap1 antibody, asap1.L antibody, asap1a antibody
Background
Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity).