ITGB1BP3 antibody (N-Term)

Catalog No. ABIN5532924

Product Details anti-ITGB1BP3 Antibody

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Binding Specificity: AA 27-55, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITGB1BP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ITGB1BP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human ITGB1BP3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ITGB1BP3

Target: ITGB1BP3 (Integrin beta 1 Binding Protein 3 (ITGB1BP3))

Alternative Name: ITGB1BP3 (ITGB1BP3 Products)

Synonyms: ITGB1BP3 antibody, MIBP antibody, NRK2 antibody, itgb1bp3 antibody, 2310015C21Rik antibody, Itgb1bp3 antibody, Mibp antibody, zgc:103408 antibody, nicotinamide riboside kinase 2 antibody, integrin beta 1 binding protein 3 antibody, nicotinamide riboside kinase 2 S homeolog antibody, NMRK2 antibody, ITGB1BP3 antibody, nmrk2.S antibody, nmrk2 antibody, Nmrk2 antibody

Background: ITGB1BP3 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The protein reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. It is involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation and may play a role in the regulation of terminal myogenesis.

Molecular Weight: 26 kDa

Gene ID: 27231

UniProt: Q9NPI5

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development