KCNA3 antibody (AA 239-268)

Catalog No. ABIN5533117

Product Details anti-KCNA3 Antibody

Target: KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))

Binding Specificity: AA 239-268

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNA3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KCNA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the Central region of human KCNA3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KCNA3

Target: KCNA3 (Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 3 (KCNA3))

Alternative Name: KCNA3 (KCNA3 Products)

Synonyms: Kv1.3-glyb antibody, kv1.3 antibody, Kv1.3B antibody, kcna3b-a antibody, HGK5 antibody, HLK3 antibody, HPCN3 antibody, HUKIII antibody, KV1.3 antibody, MK3 antibody, PCN3 antibody, Kca1-3 antibody, Kv1.3 antibody, Mk-3 antibody, cKv1.1 antibody, potassium voltage-gated channel subfamily A member 3 antibody, potassium channel, voltage gated shaker related subfamily A, member 3 S homeolog antibody, potassium voltage-gated channel, shaker-related subfamily, member 3 antibody, KCNA3 antibody, kcna3.S antibody, Kcna3 antibody

Background: Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, members of which allow nerve cells to efficiently repolarize following an action potential. It plays an essential role in T-cell proliferation and activation. This gene appears to be intronless and it is clustered together with KCNA2 and KCNA10 genes on chromosome 1.

Molecular Weight: 64 kDa

Gene ID: 3738

UniProt: P22001