KNG1 antibody (N-Term)

Catalog No. ABIN5533187

Product Details anti-KNG1 Antibody

Target: KNG1 (Kininogen 1 (KNG1))

Binding Specificity: AA 138-166, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KNG1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This KNG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids from the N-terminal region of human KNG1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Alternative Name: KNG1 (KNG1 Products)

Synonyms: BDK antibody, BK antibody, KNG antibody, Kng antibody, KNG2 antibody, fb64g01 antibody, wu:fb64g01 antibody, zgc:103569 antibody, kininogen antibody, bdk antibody, kng antibody, KNG1 antibody, IHRP antibody, KINKG antibody, KINKH antibody, Kng1 antibody, Kngk antibody, kininogen 1 antibody, kininogen 1 L homeolog antibody, inter-alpha-trypsin inhibitor heavy chain family member 4 antibody, kininogen 2-like 1 antibody, KNG1 antibody, Kng1 antibody, kng1 antibody, kng1.L antibody, ITIH4 antibody, Kng2l1 antibody

Background: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 72 kDa

Gene ID: 3827

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process