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PCDHa8 antibody (C-Term)

PCDHa8 Reactivity: Human WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN5533321
  • Target See all PCDHa8 Antibodies
    PCDHa8 (Protocadherin alpha 8 (PCDHa8))
    Binding Specificity
    • 8
    • 8
    • 7
    • 4
    AA 773-800, C-Term
    Reactivity
    Human
    Host
    • 19
    • 1
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    This PCDHa8 antibody is un-conjugated
    Application
    • 16
    • 15
    • 14
    • 14
    • 5
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This PCDHA8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-800 amino acids from the C-terminal region of human PCDHA8.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PCDHa8 Primary Antibody
  • Application Notes
    For WB starting dilution is: 1:1000

    For IHC-P starting dilution is: 1:10~50

    For IF starting dilution is: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    PCDHa8 (Protocadherin alpha 8 (PCDHa8))
    Alternative Name
    PCDHA8 (PCDHa8 Products)
    Synonyms
    PCDH-ALPHA8 antibody, protocadherin alpha 8 antibody, PCDHA8 antibody, Pcdha8 antibody
    Background
    This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
    Molecular Weight
    103 kDa
    Gene ID
    56140
    UniProt
    Q9Y5H6
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