ARHGAP10 antibody (AA 237-263)

Catalog No. ABIN5533338

Product Details anti-ARHGAP10 Antibody

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Binding Specificity: AA 237-263

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGAP10 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGAP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the Central region of human ARHGAP10.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ARHGAP10

Target: ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))

Alternative Name: ARHGAP10 (ARHGAP10 Products)

Synonyms: A930033B01Rik antibody, PSGAP-m antibody, PSGAP-s antibody, MGC78796 antibody, wu:fj86f05 antibody, zgc:136983 antibody, GRAF2 antibody, PS-GAP antibody, PSGAP antibody, Rho GTPase activating protein 10 antibody, Rho GTPase activating protein 10 S homeolog antibody, Arhgap10 antibody, ARHGAP10 antibody, arhgap10.S antibody, arhgap10 antibody

Background: GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).

Molecular Weight: 89 kDa

Gene ID: 79658

UniProt: A1A4S6