ARHGEF6 antibody (C-Term)

Catalog No. ABIN5533583

Product Details anti-ARHGEF6 Antibody

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Binding Specificity: AA 614-641, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF6 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ARHGEF6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 614-641 amino acids from the C-terminal region of human ARHGEF6.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ARHGEF6

Target: ARHGEF6 (rho Guanine Nucleotide Exchange Factor (GEF) 6 (ARHGEF6))

Alternative Name: ARHGEF6 (ARHGEF6 Products)

Synonyms: COOL2 antibody, Cool-2 antibody, MRX46 antibody, PIXA antibody, alpha-PIX antibody, alphaPIX antibody, 1600028C08Rik antibody, 1700038J06Rik antibody, 4930592P22Rik antibody, Rac/Cdc42 guanine nucleotide exchange factor 6 antibody, Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 antibody, ARHGEF6 antibody, Arhgef6 antibody

Background: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq].

Molecular Weight: 87 kDa

Gene ID: 9459

UniProt: Q15052

Pathways: Neurotrophin Signaling Pathway