Sorbs2 antibody (N-Term)

Catalog No. ABIN5533595

Product Details anti-Sorbs2 Antibody

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Binding Specificity: AA 175-204, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorbs2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ARGBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-204 amino acids from the N-terminal region of human ARGBP2.

Isotype: Ig Fraction

Application Details

Application Notes: For IF starting dilution is: 1:10~50

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for Sorbs2

Target: Sorbs2 (Sorbin and SH3 Domain Containing 2 (Sorbs2))

Alternative Name: ARGBP2 (Sorbs2 Products)

Synonyms: Argbp2 antibody, 2010203O03Rik antibody, 9430041O17Rik antibody, A530071H08 antibody, mKIAA0777 antibody, argbp2 antibody, pro0618 antibody, 9430041O17RIK antibody, DKFZp468F1119 antibody, ARGBP2 antibody, PRO0618 antibody, sorbin and SH3 domain containing 2 antibody, Sorbs2 antibody, SORBS2 antibody, sorbs2 antibody

Background: Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology(SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.

Molecular Weight: 124 kDa

Gene ID: 8470

UniProt: O94875