ART3 antibody (C-Term)

Catalog No. ABIN5533677

Product Details anti-ART3 Antibody

Target: ART3 (ADP-Ribosyltransferase 3 (ART3))

Binding Specificity: AA 280-310, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ART3 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This ART3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-310 amino acids from the C-terminal region of human ART3.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for ART3

Target: ART3 (ADP-Ribosyltransferase 3 (ART3))

Alternative Name: ART3 (ART3 Products)

Synonyms: ARTC3 antibody, 4930569O04Rik antibody, ART3 antibody, DKFZp468P1925 antibody, ADP-ribosyltransferase 3 antibody, ART3 antibody, Art3 antibody

Background: Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein. The rodent mono-ADP-ribosyltransferase RT6 is a glycosylphosphatidylinositol (GPI)-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes. The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kD and contains a hydrophobic peptide signal at its N terminus, 3 consensus motifs specific to enzymes catalyzing ADP-ribose transfer, a hydrophobic C-terminal sequence characteristic of a GPI-anchored protein, a novel motif repeated 3 times at its C terminus, and 1 potential glycosylation site.1 The ART3 and rodent RT6 proteins share 35 % amino acid identity.

Molecular Weight: 44 kDa

Gene ID: 419

UniProt: Q13508