CREB3L1 antibody (C-Term)

Catalog No. ABIN5533845

Product Details anti-CREB3L1 Antibody

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Binding Specificity: AA 481-509, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This CREB3L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 481-509 amino acids from the C-terminal region of human CREB3L1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

For FACS starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: CREB3L1 (CREB3L1 Products)

Synonyms: CREB3L1 antibody, OASIS antibody, Oasis antibody, diacylglycerol kinase-like antibody, cAMP responsive element binding protein 3 like 1 antibody, cAMP responsive element binding protein 3-like 1 antibody, LOC423198 antibody, CREB3L1 antibody, Creb3l1 antibody

Background: CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

Molecular Weight: 57 kDa

Gene ID: 90993

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding