CRISP1 antibody (C-Term)

Catalog No. ABIN5533980

Product Details anti-CRISP1 Antibody

Target: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Binding Specificity: AA 162-191, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRISP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CRISP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the C-terminal region of human CRISP1.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CRISP1

Target: CRISP1 (Cysteine-Rich Secretory Protein 1 (CRISP1))

Alternative Name: CRISP1 (CRISP1 Products)

Synonyms: AEGL1 antibody, ARP antibody, CRISP-1 antibody, HSCRISP1D antibody, HSCRISP1G antibody, HUMARP antibody, AW324342 antibody, Aeg1 antibody, AEG antibody, crisp-1 antibody, cysteine rich secretory protein 1 antibody, cysteine-rich secretory protein 1 antibody, CRISP1 antibody, Crisp1 antibody

Background: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. This protein is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head where it plays a role at fertilization in sperm-egg fusion through complementary sites localized on the egg surface. Two isoforms are encoded by transcript variants of this gene.

Molecular Weight: 28 kDa

Gene ID: 167

UniProt: P54107