CYP1A2 antibody (AA 255-282)

Catalog No. ABIN5534017

Product Details anti-CYP1A2 Antibody

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Binding Specificity: AA 255-282

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP1A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CYP1A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-282 amino acids from the Central region of human CYP1A2.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For IF starting dilution is: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.43 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CYP1A2

Target: CYP1A2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 2 (CYP1A2))

Alternative Name: CYP1A2 (CYP1A2 Products)

Synonyms: CP12 antibody, P3-450 antibody, P450(PA) antibody, CYP1A2 antibody, CYPIA2 antibody, P450-PM4 antibody, Cyp1a1 antibody, P450-3 antibody, CYPD45 antibody, P-450d antibody, RATCYPD45 antibody, CYP1A5 antibody, CP450 antibody, CYP-IA2 antibody, cytochrome P450 family 1 subfamily A member 2 antibody, cytochrome P450 1A2 antibody, cytochrome P450 LM4 antibody, cytochrome P450, family 1, subfamily A, polypeptide 2 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, cytochrome P450 1A2-like antibody, CYP1A2 antibody, LOC100328937 antibody, Cyp1a2 antibody, VDBG_06455 antibody, LOC101825565 antibody, LOC102130662 antibody

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. Other xenobiotic substrates for this enzyme include caffeine, aflatoxin B1, and acetaminophen. The transcript from this gene contains four Alu sequences flanked by direct repeats in the 3' untranslated region.

Molecular Weight: 58 kDa

Gene ID: 1544

UniProt: P05177