GJB6 antibody (N-Term)

Catalog No. ABIN5534072

Product Details anti-GJB6 Antibody

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Binding Specificity: AA 87-117, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GJB6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This GJB6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-117 amino acids from the N-terminal region of human GJB6.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.1 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for GJB6

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Alternative Name: GJB6 (GJB6 Products)

Synonyms: connexin-26 antibody, cx26 antibody, cx30 antibody, dfna3 antibody, dfna3a antibody, dfnb1 antibody, dfnb1a antibody, ed2 antibody, edh antibody, gjb6 antibody, hed antibody, nsrd1 antibody, ppk antibody, AA958971 antibody, Cx30 antibody, D14Bwg0506e antibody, CX30 antibody, DFNA3 antibody, DFNA3B antibody, DFNB1B antibody, ECTD2 antibody, ED2 antibody, EDH antibody, HED antibody, HED2 antibody, CX31 antibody, connexin 30 antibody, gap junction protein beta 2 antibody, gap junction protein beta 6 antibody, gap junction protein, beta 6 antibody, LOC387566 antibody, gjb2 antibody, GJB6 antibody, Gjb6 antibody

Background: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.

Molecular Weight: 30 kDa

Gene ID: 10804

UniProt: O95452

Pathways: Sensory Perception of Sound