CYP2B6 antibody (AA 462-488)

Catalog No. ABIN5534097

Product Details anti-CYP2B6 Antibody

Target: CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))

Binding Specificity: AA 462-488

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP2B6 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Immunogen: This P450R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 462-488 amino acids from the Central region of human P450R.

Isotype: Ig Fraction

Application Details

Application Notes: For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 2 mg/mL

Buffer: Supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Target Details for CYP2B6

Target: CYP2B6 (Cytochrome P450, Family 2, Subfamily B, Polypeptide 6 (CYP2B6))

Alternative Name: P450 (CYP2B6 Products)

Synonyms: CPB6 antibody, CYP2B antibody, CYP2B7 antibody, CYP2B7P antibody, CYPIIB6 antibody, EFVM antibody, IIB1 antibody, P450 antibody, CPF3 antibody, CYP4F antibody, LTB4H antibody, CYP2B30 antibody, CYP2B11 antibody, CYPIIB11 antibody, 21-OH antibody, 21OH antibody, 21OHA antibody, 21OHB antibody, CYP21OH-A antibody, Cyp21 antibody, Cyp21-ps1 antibody, Cyp21B antibody, Cyp21a2-ps antibody, Cyp21a2ps antibody, Oh21-1 antibody, Oh21-2 antibody, CYP2B6 antibody, cytochrome P450 family 2 subfamily B member 6 antibody, cytochrome P450 family 4 subfamily F member 3 antibody, cytochrome P450, family 2, subfamily B, polypeptide 6 antibody, cytochrome P450 family 2 subfamily B member 6 L homeolog antibody, cytochrome P450 2B11 antibody, cytochrome P450, family 21, subfamily a, polypeptide 1 antibody, cytochrome P450 subfamily 2B antibody, cytochrome P450 2B11-like antibody, CYP2B6 antibody, CYP4F3 antibody, cyp2b6.L antibody, Cyp21a1 antibody, LOC100068603 antibody

Background: P450R is an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in its gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Molecular Weight: 77 kDa

Gene ID: 5447

UniProt: P16435